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World’s First Proven Cancer Preventive?

What May Become the World’s First Proven Cancer Preventive (and Something Bigger) Ignored by Big Pharma

It is not surprising to learn that Big Pharma has shown no interest in what may become the world’s first proven cancer prevention pill. If big profits aren’t promised, pharmaceutical companies predictably pass on such a development.

The pill is a relatively safe FDA-approved generic drug, prescribed millions of times to help control diabetes, and it costs maybe 10-cents a day. But what is surprising is that public health authorities appear to be remiss in announcing this breakthrough. They are the agency in society commissioned to address important public health issues such as this.

Data has been accumulating for 5 years now showing metformin (Glucophage), an anti-diabetic drug, dramatically reduces the risk for cancer and prolongs life among patients who are battling cancer.

Graphic: courtesy Oncotarget

The data does not solely involve experiments with laboratory mice that often don’t translate to humans. The data involves human studies.

Remember the big to-do that the New York Times created in 1998 over a cancer drug that a Nobel Prize winner said would “cure cancer in two years?” (That quotation was later denied.) On the day that news story was released the stock price soared for the company making the developmental drug then said to cure cancer. But for metformin, a drug first approved by the FDA in 1958, there is little fanfare. Its patent expired years ago and it is a generic drug with low profitability. A quick check on Google shows just six news outlets online are distributing the story. Of the 7 billion people on the planet, how many will learn of this?

If this were some potential new blockbuster drug, the National Institutes of Health would be grandstanding it in a press release and even a press conference. Instead it is a news agency – in this instance Bloomberg News – who is independently breaking the story (let’s hear it for a free press). Bloomberg reporters quote a researcher who says drug companies passed up sponsorship of studies involving metformin and cancer when they realized their patents would expire before the research study was completed.

Slow progress

Frustratingly, science is moving too slowly towards adoption of such a pill. It wants to conduct another decade of research before drawing any conclusions. A number of large long-term studies are underway but not scheduled to report any data till 2016-2017.

Cancer patients haven’t ten years to wait. Whether oncologists begin to prescribe it is another question. It isn’t being heralded in oncology journals. The American Cancer Society website is ignoring this breakthrough as well.

How convincing is the evidence? Very.

Just how convincing is the currently available evidence? First, diabetics have a much higher incidence of cancer. So it should not be surprising that an anti-diabetic drug quells cancer.

Second, the risk of subsequent cancer diagnosis was significantly reduced among patients with adult-onset diabetes who took metformin. The most compliant patients were more protected against cancer than those who failed to follow their pill regimen. Another study shows an impressive 56% relative reduction in the risk for breast cancer among diabetics taking metformin compared to other anti-diabetic drugs.


Planet Earth

Meteorite explosions over Spain, Russia and the Caribbean

A bright fireball exploded over Andalusia on February 22, 2020 at about 00:22 local time. According to the first data, it was formed by rock from an asteroid, which crashed into the atmosphere at a speed of about 43,000 km / h.

The decay began at an altitude of 70 km above Almeria (Andalusia) and ended at an altitude of 29 km above the Mediterranean Sea.

Cameras in Calar Alto (Almeria), Sierra Nevada (Granada), La Hita (Toledo) and Seville recorded bright meteorite decay.

A huge meteorite fireball replaced night to day on February 21, 2020 at 4:35 local time in the Segezha district of the Russian Republic of Karelia. After a bright flash of light, a loud booming sound was heard.

On February 21, a large cosmic rock exploded over the Caribbean Sea. The explosion was so vivid that cameras in Puerto Rico filmed it.

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Planet Earth

How much snow has melted due to record high temperatures in Antarctica?

Antarctica has long been considered the coldest place on our planet, but now it cannot be called that. It is believed that the average annual temperature on a snowy continent should be approximately -57 degrees Celsius.

However, on February 6, 2020, the territory of Antarctica was in a fixed record high air temperature of 18.3 degrees Celsius. These data were provided by employees of the Esperanza research station, which is located in the far north of the Antarctic Peninsula. Warm weather lasted about a week and it provoked the melting of a fairly large amount of snow. The effects of record air temperatures are especially noticeable on Eagle Island, whose snow cover has melted greatly.

Melting ice in Antarctica can kill many species of animals

The consequences of warming in Antarctica were described in the scientific publication Sciencelert. Eagle Island is located near a part of the Antarctic Peninsula, referred to as Graham Land. At the end of 2019, the island was covered with snow and ice, but now, due to the sudden warming of the air, it looks like an ordinary patch of moist land with snowy patches. In addition, ponds formed from melted ice in its center, which cannot drain into the sea.

The effects of warming in Antarctica

The effects of an increase in air temperature in Antarctica are clearly visible in the images sent by the Landsat 8 satellite. They clearly show how, in just a dozen days, Eagle Island lost a huge part of the ice cover. It is reported that during this short period of time the island lost about 10 centimeters of snow and ice. According to glaciologist Mauri Pelto, who has been studying natural ice for many years, melting of ice and snow in such a speed has never been observed in Antarctica. At least, he had not yet encountered such phenomena.

As a rule, the ice of Greenland melts most and most noticeably. We were made sure about this fact  back in 2015, when a group of scientists led by Eric Rinho from the University of California came to this conclusion. Moreover, some scientists are confident that due to the gradual increase in the temperature of the Earth’s air, Greenland may soon completely lose its ice cover. This threatens that the level of the oceans will rise dramatically, which will harm both people and animals.

Eagle Island taken on Landsat 8 satellite

Glaciologist Mauri Pelto also emphasized that it was scary not that the ice on Eagle Island had melted so quickly, but that such events were happening more and more often. The previous temperature record in Antarctica was recorded on March 24, 2015, when the air warmed up to 17.5 degrees Celsius. In 2020, the air temperature was as much as 18.3 degrees Celsius. What surprises will be presented to us by nature in the future, no one knows. Perhaps we are waiting for new temperature records, and the melting of ice and snow on Eagle Island is just nothing compared to what is coming.

In general, scientists from the University of California at Davis believe that nothing good awaits people in the future. According to them, humanity will boil alive, like “frogs in boiling water.”

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Planet Earth

An engineer who believed in the theory of a flat earth died when his rocket was launched

Mike Hughes, nicknamed Mad Mike, a well-known amateur engineer flying on makeshift rockets, died during one of his experiments on Saturday in the United States, the Los Angeles Times reported citing his agent.

Mad Mike was remembered by the general public for his faith in the theory of a flat Earth. In 2018, he told the Associated Press that the Earth was “Frisbee-shaped” and that he intended to fly into space to make sure it was.

On Saturday, Hughes planned to climb five thousand feet on his makeshift desert rocket near the town of Barstow, California. The event was supposed to be shown in the special program “Home Astronauts”. 

The video of spectators who arrived to watch the launch captures the launch of his rocket, the parachute that did not work on time and the fatal fall of the amateur astronaut.

Mike’s agent suggested that Mike might have lost consciousness during the launch of the rocket and as a result did not activate the parachute. He fell 2600 feet from the place where the rocket was launched.

It is worth noting that Mike was going to launch his home-made steam rocket in August last year, but as a result, his plans were postponed.

For decades, Hughes has performed tricks from jumping in a limousine over long distances to flying on rockets made from improvised materials. In 2018, Mike’s rocket rose to a height of 1.9 thousand feet and then landed in the Mojave Desert.

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