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They have discovered the secret of longevity and it is not a rejection of bad habits

Japanese scientists have examined more than 40,000 cells taken from many older adults over the age of 50.Among these people are seven “extra-long lives” who have passed their 110th anniversary. A unique immune system has been found in their blood, which effectively fights cancer cells and dangerous infections.

Most often, centenarians wonder what they eat and what their lifestyle is. It usually turns out that neither cigarettes nor alcohol prevent them especially from reaching adulthood. Also, longevity is not affected by special diets.

Now, scientists are learning that the key to longevity is not a lifestyle, but the presence of a special immune system. Seven Japanese superlongs have been found in the blood of more than ordinary whites T cells or CD4 cells that “hunt” viruses and cancer cells.

Each has a significant amount of these cells. These are the so-called T-helper or T-lymphocyte. They help other white blood cells fight infections.

But firstly, in the blood of these perennials are found much more than the norm of these T-cells and secondly, they have been so “toxic” that, in addition to infections, they aim to find and destroy potential cancer cells.

Such an immune system has helped these centenarians to live for over a hundred years without any problems. These people do not even have heart diseases.

This important study was conducted by specialists at the RIKEN Center for Integrative Medicine in Japan, Keio University (Keio University).

The lead scientist of the study – Dr. Kosuke Hashimoto says:

“Long-lived people usually spend their entire lives in good health. Their strong immune system protects them perfectly against tumors and infections. “

It seems that having such an immune system in the body is an innate genetic trait that gives these people a great advantage.

Some of the oldest people on the planet, such as Frenchwoman Jeanne Calment and American Richard Overton, have smoked and abused alcohol throughout their lives that has not affected their health.

Jeanne Kalman died in 1997, at the age of 122. You can find her pictures on the internet during her 117th birthday celebration. They are seen smoking as a steam engine and in good health. In addition, Kalman adored wine, olive oil and chocolate, considering these habits as key to her longevity.

Jeanne Kalman

Richard Overton died at the age of 112.

Richard Overton

Other centenarians say the key to sound health is through special diets, exercise, regular work, regular sex, avoiding stress, praying, observing moral principles, bathing frequently in hot tubs and even eating pig feet. In essence, all this turns out to be self-belief.

Pierre Carnancy, Deputy Director of the RIKEN Center says:

“We believe that the type of cells we find is a true guarantee of many years of life and good health, protecting organs from cancer and other diseases.”

That study is published in the journal Proceedings of the National Academy of Sciences (PNAS).

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Science & Technology

Future hyperreality: Prototype of a smart contact lens

Mojo Vision, a newly created technology company, has presented a functional prototype of what claims to be the world’s first truly intelligent contact lens.

This smart lens is essentially a miniaturized screen that can be worn in the eye. The company says it could provide directions, sports results or even let you see in the dark. Essentially, it is a mini computer. The best part of this? No one will ever know it’s there! It has been designed so that people cannot see it and, according to the senior vice president of product and marketing, Steve Sinclair, the company has done it in such a way that the interactions are also extremely subtle, made only with eye movements, ensuring that no one notices their presence.

It goes without saying that this type of technology has many uses and the possibilities are endless. However, there is still a lot of work to do before it can be released, including full FDA approval that adheres to regulations and standards, something the company is currently working on.

Specifications

In addition to being invisible, the contact lens will also be discreet. It is possible that a screen just in front of the eye is constantly feeding the information, which is not what the company wants. Therefore, it will only give the user the data they need and when they need them, instead of bombarding them with them when they do not need them. This is especially important, since the screen will remain visible when the eyes are closed because it is a contact lens.

The technology behind all this is also extremely interesting. Right in the center of the smart lens is a miniature MicroLED screen that has a pixel density of 14,000 pixels per square inch (ppi), which is actually a world record according to the company.

For a quick comparison, the crystal screen of the retina of the new iPhone 11 has a pixel density of only 323 ppi, which is tiny compared to the lens.

Although it looks like something straight out of a James Bond movie, this contact lens is on its way to becoming a reality and may not be as far away as many people think. While it is still in its prototype stage, it is fully functional. Apart from FDA approval and filing some rough edges, it is almost ready to work. The final product, which will be aimed at the visually impaired, could change people’s lives forever, which is a very exciting perspective!

This is a vision of our future hyperreality:

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Scientists decoded the giant squid genome and saw that this creature has a very developed brain

Giant squids of the genus Architeutis are one of the largest invertebrate creatures, which, according to official data, can reach about 8-10 meters in length, and twice as much according to unofficial ones.

Pictures of live squids were first obtained by Japanese researchers in 2004, before that scientists had ideas about giant squids only from their remains found in the stomachs of sperm whales or washed ashore.

Until now, not a single giant squid fell into the hands of scientists, which is associated not only with the fact that these creatures live mainly at great depths, but that that they rarely swim to the surface, as they sperm whale’s favorite treat.

A relatively small giant squid of the Architeuthis dux species, reaching a length of “only” 4 meters

The genome of giant squid was analyzed by a team of researchers from the University of Copenhagen (Denmark), as well as researchers from the Marine Biological Laboratory of the State of Massachusetts under the leadership of Caroline Albertin. In total, this group sorted the genomes of several cephalopods at once, including octopus, cuttlefish and nautilus mollusk.

DNA samples of a giant squid were taken from a frozen piece of flesh of this creature, found many years ago on the ocean and preserved in one of the laboratories.

Researchers first found that the size of the giant squid genome is not that far behind the human genome. The giant squid had about 2.7 billion complementary pairs of DNA, which is about 90% of the human genome.

Although the size of the genome is not necessarily related to the creature’s complexity and intellectual development, more than a hundred giant squid genes have been linked to a family of specific protocadherin proteins that are responsible for complex brain structure.

The remains of a giant squid at the Smithsonian Museum.

According to Caroline Albertin, as a rule, these proteins are found in very little (or not at all) in invertebrates, and the presence of more than 100 protocadherins in the giant squid genome can be compared to the finding of a “smoking gun”, because this directly indicates that these creatures are very smart.

By the way, in the octopus genome in 2015, the same proteins were also found in approximately the same amount.

Other unusual finds include a unique set of genes responsible for the growth and development of giant squid, which were not in the genome of octopus, cuttlefish and nautilus. This probably explains why giant squids grow so huge.

The results of this curious study were published in the scientific journal GigaScience.

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Science & Technology

Abnormal particles whose origin remains inexplicable

Photo: Icecube / NSF

An international team of scientists has detected abnormal particles whose origin remains inexplicable. The discovery, which can refute modern ideas about particle physics, is reported in a preprint published in the arXiv.org repository .

Researchers have discovered several neutrino candidates using ANITA atmospheric probes (Antarctic Impulsive Transient Antenna). Two of the three events, which are interpreted as tau neutrinos, turned out to be associated with the atmospheric shower of high-energy particles that arose during the interaction of the Earth’s atmosphere with tau leptons. The latter flew out of the core of the Earth, with which tau neutrinos interacted, which came from the other side of the planet.

The third possible neutrino was found during the search for the Askaryan effect – radiation that occurs when particles at light speeds pass through the Earth’s substance. However, scientists also did not exclude that this event is associated with background radiation.

Physicists tested the hypothesis that all recorded neutrinos were of cosmic origin and originated in natural accelerators (for example, blazars). In this case, a secondary stream of low-energy neutrinos should have arisen, to which IceCube detectors with certain characteristics are sensitive. The data collected by the under-ice neutrino observatory over seven years were analyzed, but no signs of such a flow were found.

High-energy neutrinos were first detected by IceCube detectors in 2013. It is believed that part of these particles is born from the interaction of cosmic rays and matter (or radiation fields) in the vicinity of natural cosmic accelerators. Another type of high-energy neutrino occurs when cosmic rays interact with the cosmic microwave background. These particles pass through the Earth from all directions in a uniform flow.

According to scientists, the origin of the recorded neutrino candidates cannot be explained within the Standard Model. In the case of a uniform flow, ANITA was supposed to record similar events from different viewing angles. No possible neutrino source was also found in the direction for the neutrino candidate resulting from the proposed Askarian effect. However, these anomalies can be explained by new physics, which suggests the presence of axionic and heavy dark matter, sterile neutrinos, and supersymmetries.

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