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The World’s First Reprogrammable DNA Computer is Here

Flexible Strands

A stark limitation to biological computers was that any code programmed into DNA couldn’t be rewritten. UC Davis computer scientist David Doty told Wired that using a DNA computer is “like having to build a new computer out of new hardware just to run a new piece of software.”

But now, Doty and his team have built the first DNA-based computer that can be written and rewritten like any other — a potentially revolutionary leap that could lead to the next generation of biological computing.

Building Blocks

In research published Wednesday in the journal Nature, Doty and other scientists from UC Davis, California Institute of Technology, and Harvard describe a DNA-based computer with 355 different “tiles” of DNA that can be compared to the circuits in a conventional computer.

Compared to existing DNA circuitry that can only one run program, the team of researchers managed to program their computer to run 21 different programs, which can do simple things like counting, selection options from a list, and recognizing palindromes.

It’s all early work — Wired describes the study as producing “beautiful, albeit useless results” — but it could lay the groundwork for a new generation of flexible, programmable biological computers.

New Standard

Conventional computers still have a major advantage over DNA-based systems, in part because of how much of a head start they have. Your laptop has decades of development behind it, so the people writing new programs don’t need to also study materials science, circuitry, and all of the other various disciplines that led to the first computer.

But as research like Doty’s develops and more team of scientists build on the work, that may change — Wired envisions a future where molecular programmers can approach their trade with just as narrow and specialized a focus as today’s computer scientists can.

READ MORE: Finally! A DNA Computer That Can Actually Be Reprogrammed [Wired]

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Science & Technology

Scientist Peter Scott-Morgan is set to become “the world’s first complete cyborg”

Scientist and roboticist Peter Scott Morgan, who is using an advanced version of Stephen Hawking's communication system, built by Intel. INTEL

Two years ago scientist Peter Scott-Morgan was diagnosed with motor neuron disease, also known as Lou Gehrig’s disease, and today he is still fighting for a new life, not just for survival.

This October, Dr. Scott-Morgan is on track to become the world’s first full-fledged cyborg, potentially giving him more years of life.

The world’s first complete cyborg

It was in 2017 that Dr. Peter Scott-Morgan (a brilliant robotics writer, scientific writer, and talented speaker) was diagnosed with degenerative motor neuron disease that ultimately paralyzed his entire body except his eyes.

The diagnosis is understandably grim, especially considering that he has only two years to live, but he has not given up the fight.

Teaming up with world-class organizations with expertise in artificial intelligence, Dr. Scott-Morgan is transforming himself into what he calls “the world’s first fully fledged cyborg.”

“And when I say ‘Cyborg’, I mean not just that some kind of payment will be implanted in me, I mean that I will become the most advanced human cybernetic organism ever created on Earth for 13.8 billion years. My body and brain will be irreversibly changed, ”says Dr. Scott-Morgan.

What does it mean to be human

According to Dr. Scott-Morgan, he will become part robot and part living organism. Moreover, the change will not be one-time, but with subsequent updates.

“I have more updates in the process than Microsoft ,” says Dr. Scott-Morgan.

AI-powered creative expression

The cyborg artist is a great example of the power of human-AI collaboration. AI uses the data that make up Peter’s digital portrait ( articles, videos, images, and social media ) and is trained to recognize key ideas, experiences, and images.

Peter will introduce a theme, AI will suggest composition, and Peter will apply images to suggest style and mood. Peter will direct the AI ​​to render a new digital image that none of them could create alone.

A unique blend of AI and human, reflects Peter’s creative and emotional self – a critical aspect of what it means to be human.

Peter 2.0

This October, Dr. Scott-Morgan will undergo what he calls the latest procedure that will transform him into “Complete Cyborg”.

October 9 he tweeted a photo of himself, writing the following:

“This is my last post as Peter 1.0. Tomorrow I will trade my vote for potentially decades of life as we complete the last medical procedure for my transition to Full Cyborg, in the month that I was told statistically I would be dead. I am not dying, I am transforming. ! Oh, how I LOVE science !!! “.

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Japan has developed an inflatable scooter that weighs practically nothing

The University of Tokyo engineers have developed the Poimo inflatable electric scooter, which is created individually for each owner. It is enough to send your photo to the manufacturers – and a personal optimized model will be assembled for you.

The scooter is designed with a special program for the body size of a particular user and his specific fit. Moreover, each owner is free to make any changes to this model. If he makes any changes to the drawing, the program will automatically redesign the electric bike to maintain its strength, stability and controllability. When the model is finished and approved, it is handed over to the manufacturer.

Scooter Poimo

The scooter consists of seven separate inflatable sections that are constructed from durable fabric and sewn with straight stitch. It remains to add electronic components – in particular, a brushless motor and a lithium-ion battery. 

The finished electric scooter weighs about 9 kg and can travel at speeds up to 6 km / h (that is, slightly faster than a pedestrian). It can work for an hour on one charge.

This is how the current version of Poimo looks like in action:

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Excerpts from Elon Musk’s speech at the Martian Society convention

Elon Musk’s comments with questions relayed from the Mars Society Membership by Dr. Robert Zubrin, James L. Burk, and Carie Fay. Following Elon’s 30 min time, Dr. Zubrin took additional questions. This special event was part of the 2020 Mars Society Virtual Convention from October 14-18, 2020.

About Starship Test Schedule:

– entering orbit – with a probability of 80% -90% will take place in 2021

– the probability of the return of the ship and the 1st stage in this flight is 50%

– test of refueling in orbit – 2022

– Starship lunar version – 2022 or 2023

– Starship flight to Mars – around 2024

The goal of the Starship is to build a self-sufficient settlement on Mars as quickly as possible. Musk does not rule out the possibility that this will not be achieved during his lifetime. According to his rough estimates, to create a self-sufficient city, it will be necessary to deliver 1 million tons of cargo, which corresponds to 4-5 million tons in a low Earth orbit. Modern single-use launch vehicles are capable of removing less than 1% of this value.

“Disposable launch vehicles are completely stupid. They are a waste of time. I think people need to stop wasting time on this. If you try to sell a disposable plane, you will be thrown out of the office. If you try to sell a disposable car, you will also be thrown out of the office. “

A series of questions and answers followed:

What is the best landing site on Mars?

– I’m not sure about that. But I can name the criteria. The first of these is latitude: most likely it will be in the northern hemisphere, far enough to the north to have water ice, but to still have enough sunlight.It also needs to be low to get the most benefit from atmospheric braking.

How do you prioritize mission priorities: research, infrastructure construction, and science?

– The first will be the construction of a fuel plant.

A question from a teenager who wants to become an engineer and robot maker with a dream to work at SpaceX: what is the most important education in order to become an engineer?

– There are many varieties of this profession: you can be an aerospace engineer, in the field of electronics, software, or a chemical engineer involved in creating safe production of fuels. I think physics is a good foundation for critical thinking.

Boring Company was originally conceived as a tunnel manufacturing firm on Mars?

– No. It was originally something of a joke. I thought tunnels were a good solution to reduce the traffic problem in cities and improve the quality of life by turning parking lots into green parks. To do this, you need to go to 3d [get away from the “flat” infrastructure – approx. per.]. I think tunnels are good for Mars too. But there you need a lot lighter equipment: you don’t care about mass on Earth, but you will have to take care of it a lot when going to Mars.

At Boring Company, have you learned a lot of technology that might come in handy on Mars?

– I think, yes.

Do you have any tips for young people who love Mars but don’t know how to participate in its settlement?

– I think any strong advocate of the need to conquer Mars matters. People often don’t even think about it. I often talk to people who don’t even know about it. Therefore, I consider it important for humanity and consciousness in general to bring a discussion about this to society. Talking about it with friends and acquaintances – I think this is what we should do. In my estimate, we will spend less than 1% of our efforts on Mars exploration, exactly less than healthcare, perhaps even less than cosmetics – this will be enough to make life multi-planetary. But this requires people to start talking about it 100 times more often. I think this is what really matters. [the entire cosmonautics of the world is $ 424 billion a year, while cosmetics is $ 532 billion, and tobacco production is $ 849 billion – approx. per.]

What’s the coolest part about Starship development?

– I think the coolest detail is the ability to work with a great group of engineers and come up with interesting solutions. I think the best thing is the opportunity to work with smart and creative people who come up with solutions that were not available before. This is a great reward.

What do you focus on when hiring, especially with regard to engineers?

“We’re looking for signs of exceptional ability. Or at the very least, striving to do exceptional things at SpaceX.

Are you planning to make a Mars-Earth communication system like Starlink?

– Yes, I think we will use a laser, probably launched into orbit, to avoid atmospheric diffraction. Thus, it will be a laser beam going from the orbit of the Earth to the orbit of Mars. And also relay satellites in solar orbit, since the laser beam cannot be sent through the Sun [when it is between Mars and Earth – approx. per.].

Can Starship be used for other destinations like Venus and other planets?

– Starship will be able to travel to any target in the solar system that has a solid surface when fuel depots appear. It is not the kind of transport that will take us to other stars, but when we become a multi-planetary species, we will create a demand for innovation in space travel that will ultimately lead us to interstellar travel.

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