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First interview with a dead man

Name: Graham Condition: Cotard’s syndrome
“When I was in hospital I kept on telling them that the tablets weren’t going to do me any good ’cause my brain was dead. I lost my sense of smell and taste. I didn’t need to eat, or speak, or do anything. I ended up spending time in the graveyard because that was the closest I could get to death.”
Nine years ago, Graham woke up and discovered he was dead. He was in the grip of Cotard’s syndrome. People with this rare condition believe that they, or parts of their body, no longer exist.
For Graham, it was his brain that was dead, and he believed that he had killed it. Suffering from severe depression, he had tried to commit suicide by taking an electrical appliance with him into the bath.
Eight months later, he told his doctor his brain had died or was, at best, missing. “It’s really hard to explain,” he says. “I just felt like my brain didn’t exist anymore. I kept on telling the doctors that the tablets weren’t going to do me any good because I didn’t have a brain. I’d fried it in the bath.”
Doctors found trying to rationalise with Graham was impossible. Even as he sat there talking, breathing – living – he could not accept that his brain was alive. “I just got annoyed. I didn’t know how I could speak or do anything with no brain, but as far as I was concerned I hadn’t got one.”
Baffled, they eventually put him in touch with neurologists Adam Zeman at the University of Exeter, UK, and Steven Laureys at the University of Liège in Belgium.
“It’s the first and only time my secretary has said to me: ’It’s really important for you to come and speak to this patient because he’s telling me he’s dead,’” says Laureys.
Limbo state
“He was a really unusual patient,” says Zeman. Graham’s belief “was a metaphor for how he felt about the world – his experiences no longer moved him. He felt he was in a limbo state caught between life and death”.
No one knows how common Cotard’s syndrome may be. A study published in 1995 of 349 elderly psychiatric patients in Hong Kong found two with symptoms resembling Cotard’s (General Hospital Psychiatry, DOI: 10.1016/0163-8343(94)00066-M). But with successful and quick treatments for mental states such as depression – the condition from which Cotard’s appears to arise most often – readily available, researchers suspect the syndrome is exceptionally rare today. Most academic work on the syndrome is limited to single case studies like Graham.
Some people with Cotard’s have reportedly died of starvation, believing they no longer needed to eat. Others have attempted to get rid of their body using acid, which they saw as the only way they could free themselves of being the “walking dead”.
Graham’s brother and carers made sure he ate, and looked after him. But it was a joyless existence. “I didn’t want to face people. There was no point,” he says, “I didn’t feel pleasure in anything. I used to idolise my car, but I didn’t go near it. All the things I was interested in went away.”

Visiting a graveyard was “the closest I could get to death”, Graham says

Even the cigarettes he used to relish no longer gave him a hit. “I lost my sense of smell and my sense of taste. There was no point in eating because I was dead. It was a waste of time speaking as I never had anything to say. I didn’t even really have any thoughts. Everything was meaningless.”
Low metabolism
A peek inside Graham’s brain provided Zeman and Laureys with some explanation. They used positron emission tomography to monitor metabolism across his brain. It was the first PET scan ever taken of a person with Cotard’s (Cortex, DOI: 10.1016/j.cortex.2013.03.003).
What they found was shocking: metabolic activity across large areas of the frontal and parietal brain regions was so low that it resembled that of someone in a vegetative state.

Read the full article at: newscientist.com

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This is the world’s first commercial flying car

The world’s first commercial flying car is already on sale. It is equipped with two retractable propellers and rear wings.

The vehicle was presented during the Miami Art Week 2019 by the Dutch company PAL-V International. It is called Liberty, and its price is around 600,000 dollars.

It has Dutch engineering and Italian design, it is already in active production and has at least 70 anticipated.

“As soon as Nicolas Cugnot invented the car and the Wright brothers made their first successful flight, people began to dream of combining the two in a flying car.”

‘It turned out to be more complicated than initially estimated: a complex puzzle. However, once resolved, it would create maximum freedom in mobility’, said the executive director of the company, Robert Dingemanse.

PAL-V Flying car "width =" 780 "height =" 390 "
Credit: pal-v.com

When will it be available?

The first units are expected to reach their owners in 2021. However, it must be borne in mind that to handle it, it is necessary to have not only the driver’s license, but also the pilot’s license.

The new car has two versions, the Pioneer and the sports version. Robert Dingemanse explained that the Pioneer version differs from Liberty by its a complete carbon package. He also revealed that only 90 flying cars will be manufactured in this version.

Features of the flying car

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PAL-V Pioneer. Credit: pal-v.com
Inside of the flying car "width =" 1104 "height =" 736 "srcset ="
Interior of the flying car. Credit: pal-v.com

The PAL-V, a three-wheeled vehicle that can carry up to two passengers and 20 kilos of cargo, is basically a hybrid between a car and a helicopter.

According to the company website, the PAL-V has a four-cylinder engine and is capable of flying at an altitude of up to 3,500 meters. The vehicle, which is made with carbon fiber, titanium and aluminum and weighs only 664 kilograms, uses gasoline for cars and can reach maximum speeds of 180 km / h in the air and 160 km / h on land.

It also has both a ground and air system similar to that of a motorcycle in which the pilot-driver tilts the machine with a control lever.

It also stands out that the PAL-V converts from car to gyrocopter in just 10 minutes and can accelerate from 0 to 100 km / h in less than 9 seconds.

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Health authorities have confirmed a case of a rare type of smallpox in a UK patient

Skin rashes caused by ape pox. Credit: CDC's Public Health Image Library (Public domain)

A patient in England has been diagnosed with a rare case of monkeypox, as reported by Public Health England (PHE).

The rare viral infection is similar to smallpox, and though it is milder, it can be fatal.

It has been reported that the individual was in Nigeria and that he would have contracted the disease there. Later, upon returning to the United Kingdom, he stayed in the southwest of England where the disease occurred.

Upon symptoms, he was transferred to the Guy’s and St Thomas’ NHS Foundation Trust , a center specializing in infectious diseases in London.

The health authorities have taken the necessary measures to prevent the virus from spreading to other people.

Vaccination against smallpox to people in Africa. (Public domain)

The PHE said in a statement:

As a precaution, PHE experts are working closely with NHS colleagues to implement rapid infection control procedures, including contact with people who may have been in close contact with the individual to provide health information and advice. ”

But experts are not very worried about contagion, because monkeypox does not spread easily among people and the risk of affecting the population is quite low, said Dr. Meera Chand , PHE consulting microbiologist.

This transmission electron micrograph (TEM) represents a series of smallpox virus virions. Credit: CDC / Dr. Fred Murphy; Sylvia Whitfield / Wikimedia Commons

Although the infection usually occurs mildly and people get better without treatment; Some individuals may develop very serious symptoms, with a percentage of 1 to 10 percent of patients dying from the disease during outbreaks, according to the World Health Organization .

The symptoms presented are similar to those of smallpox but milder. First, fever, headaches, muscle aches, back pain, swollen lymph nodes, chills and exhaustion. Subsequently rashes may appear on the skin , starting on the face and spreading throughout the rest of the body.

This is not the first time a patient has been infected with smallpox in the United Kingdom. In 2018, there were three cases after a person was diagnosed with the disease. The individual had also returned from Nigeria.

Source: Gov.ukIFL Science

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A cold virus can infect a pregnant woman’s fetus

The study showed that the expectant mother is able to transmit a respiratory tract infection to her unborn child.

Scientists from Tulane University (Louisiana, USA) received the first evidence that the cold virus, which affects a pregnant woman, can penetrate the placenta and infect the fetus. An article about this has been published in PLOS One .

The placenta, an organ that develops in the uterine cavity of a woman during pregnancy, provides the necessary nutrition from the mother to the embryo and simultaneously performs another important task: it filters out potential pathogenic microorganisms. However, a group of pediatricians led by Professor Giovanni Piedimonte found that this natural “barrier” is not so impenetrable.

Scientists took the placenta from donors, isolated three main types of cells – cytotrophoblasts, fibroblasts and Kashchenko – Hofbauer cells – and in vitro exposed them to the human respiratory syncytial virus, which causes respiratory tract infections. Although cytotrophoblast cells supported a weak process of the spread of the virus, two other types were more susceptible to infection. So, Kashchenko-Hofbauer cells survived and allowed the virus to replicate inside the cell walls. According to scientists, then these cells, moving inside the placenta, are able to transmit the virus to the fetus.

“Such cells do not die after they become infected,” Piedimonte explains. – When they enter the fetus, they are comparable to bombs stuffed with a virus. They do not spread the virus in the area of ​​the “explosion”, but carry it through the intercellular channels. <…> Thus, our theory is confirmed that when a woman gets a cold during pregnancy, the virus that causes the infection can pass to the fetus and cause a pulmonary infection before the birth of a child. ”

Pediatricians also suggested that the respiratory syncytial virus is able to infect the lung tissue of the unborn baby and provoke the development of an infection that will subsequently affect the predisposition to asthma. To confirm or refute their theory, the authors of the study intend to conduct clinical tests.

Last year, scientists from the University of Cambridge created an artificial and functional mini-placenta using trophoblasts, and recently it turned out that particles of air pollution can penetrate the placenta of pregnant women

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